Effect of percutaneous coronary intervention in diabetic patients with non-ST elevated myocardial infarction
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Abstract
Background:Diabetic patients with Non ST Elevated Myocardial Infarction (NSTEMI) are at high risk for subsequent cardiovascular events. But, early Percutaneous Coronary Intervention (PCI) in high risk group of NSTEMI patients significantly prove the primary outcomes.
Objective: The aim of the study was to evaluate the changes in Left Ventricular (LV) systolic function after successful PCI in diabetic patients with NSTEMI compared to non diabetic group.
Methods: From January 2018 to December 2018, this comparative clinical study was carried out in the Department of Cardiology, Bangabandhu Sheikh Mujib Medical University (BSMMU), Dhaka, Bangladesh. Diabetic and non-diabetic patients (30 and 34 respectively) with NSTEMI undergoing PCI were included in the study. Successful PCI with drug eluting stent was performed for all patients. Transthorasic echocardiography was done at baseline, at discharge following PCI and 3 months thereafter to measure the LV systolic functions and compare them between diabetics and non-diabetic group to assess the outcome of intervention.
Results: At baseline Left Ventricular Ejection Fraction (LVEF) was somewhat lower in diabetic group than that in non-diabetic group. Three months after PCI, LVEF improved 8.4±1.2% in dibetics and 7.9±1.2% in non dibetics but the difference of this improvement between two groups was not statiscally significant (p = 0.631).
Conclusion: Statistically similar improvement was observed in left ventricular systolic function after PCI with stenting in diabetic and non diabetic patients with NSTEMI. So, indications of PCI with stenting may be extended in diabetic patient with NSTEMI.
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